Value of interleukin 4 and immunoglobulin E levels monitoring in diagnosis of drug allergy reaction
- VernacularTitle:白介素-4和免疫球蛋白E含量监测在药物过敏反应诊断中的应用价值
- Author:
Zhiyong LI
;
Yangling WU
;
Shaobin CAI
- Publication Type:Journal Article
- Keywords:
interleukin 4;
immunoglobulin E;
drug allergy reaction
- From:
Chinese Journal of Biochemical Pharmaceutics
2015;(11):30-32
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore interleukin 4 and immunoglobulin E levels indicators monitoring value in diagnosis of drug allergy reaction . Methods The way of intravenous injection and conventional intraperitoneal injection was used, with the corresponding drugs such as saline, horse serum sensitized, and in different time interleukin -4 and total immunoglobulin E index were recorded in guinea pig serum.Results Injection of saline and Chuankezhi injection, interleukin-4 and total immunoglobulin E protein content , the difference was not statistically significant, but in other drug induced sensitive D8, D14 and D21, interleukin-4 and total immunoglobulin E protein content increased significantly.Conclusion Interleukin 4 and immunoglobulin E levels index detection is the diagnosis of drug allergy is an effective and fast way .
