The correlation between diabetes and pancreatic cancer and the imaging findings

VernacularTitle:胰腺癌与糖尿病的相关性及其影像学评价
Author: Xiaoshuang LI ; Zhongqiu WANG
Publication Type:Journal Article
Keywords: Pancreatic cancer; Diabetes; Correlation; Molecular imaging
From: Journal of Medical Postgraduates 2015;(11):1223-1227
CountryChina
Language:Chinese
Abstract: Diabetes mellitus ( DM) is widely considered to be associated with pancreatic cancer ( PC) .Some studies have shown that DM has been recognized as a risk factor for PC and the early clinical manifestation of PC , however the exact relationship re-mains unclear .The conventional imaging techniques and molecular imaging techniques can evaluate the abnormal condition during the occurrence and development of PC and diabetes .This article will review the correlation between PC and DM and the potential molecular mechanism, such as hyperglycemia, insulin-like growth factors, oxidative stress, islet amyloid polypeptide and Kruppel sample factorⅡgene mutations, etc.In addition, the value of imaging diagnosis for PC and DM is also reviewed .