Correlation of a high normal serum TSH with blood pressure, fasting plasma glucose, and blood lipids in Chinese Han population

VernacularTitle:中国汉族人群高TSH水平与血压、空腹血糖及血脂的相关性研究
Author: Quhua YIN ; Ming ZHAN ; Dongmei KANG ; Jun LIANG ; Huaidong SONG
Publication Type:Journal Article
Keywords: Thyroid-stimulating hormone; Systolic blood pressure; Fasting plasma glucose; Lipids
From: Chinese Journal of Endocrinology and Metabolism 2015;(9):781-783
CountryChina
Language:Chinese
Abstract: [Summary] A total of 1 510 subjects undergoing physical examination in the Central Hospital of Xuzhou were included in this study. According to the level of TSH, the subjects were divided into low TSH group(0. 30-0. 99 mIU/L,n=351), moderate TSH group(1. 00-1. 89 mIU/L, n=703), and high TSH group(1. 90-4. 80 mIU/L, n=456). Analysis of variance and linear regression were used for data analysis. The results showed that systolic blood pressure ( SBP) , diastolic blood pressure ( DBP) , triglyceride ( TG) , and high-density lipoprotein cholesterol( HDL-C) revealed significant differences among 3 group(P<0. 05 or P<0. 01). In the univariate linear regression model, serumTSHwithinthereferencerangewasnegativelyassociatedwithSBPandDBP(P<0.05orP<0.01),and positively associated with TG and HDL-C (P<0. 05 or P<0. 01). However, the correlations disappeared after adjustment for gender, age, body mass index, fasting plasma glucose ( FPG ) , and TG. In the multiple linear regression model, a significant negative correlation of TSH with SBP and FPG was found in males(P<0. 05).