Preparation and Characterization of Berberine Hydrochloride Ternary Complexes
10.11842/wst.2014.10.026
- VernacularTitle:盐酸小檗碱脱苦三元复合物的制备及其表征
- Author:
Zhongyi ZHANG
;
Panpan ZHANG
;
Wenjie ZHANG
;
Pinfeng ZHANG
;
Ruixin LIU
- Publication Type:Journal Article
- Keywords:
Berberine hydrochloride;
β-cyclodextrin;
whey protein isolate;
taste-masking;
debitterizing ternary complexes
- From:
World Science and Technology-Modernization of Traditional Chinese Medicine
2014;(10):2208-2213
- CountryChina
- Language:Chinese
-
Abstract:
The debitterizing effect of ternary complexes was appraised and characterization of ternary complexes was made by infrared spectrum (IR) and differential scanning calorimetry (DSC). The ternary complexes (β-CD/BH/WPI90) of berberine hydrochloride (BH),β-cyclodextrin)β-CD (and whey protein isolate (WPI90) were prepared with adopting coprecipitation preparation. The results showed that the ternary complexesβ-CD/BH/WPI90 can sig-nificantly reduced the bitterness of BH. The content of BH in the ternary complexes was 3.20%. It was concluded that the ternary complexesβ-CD/BH/WPI90 had significant effect in reducing the bitterness of BH. IR and DSC of the ternary complexesβ-CD/BH/WPI90 were different from the simple physical mixture.
