Effect of integrative cognitive training on mild cognitive impairments: a one-year follow-up study
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3760/cma.j.issn.0254-9026.2015.04.004
   		
        
        	
        		- VernacularTitle:综合认知训练对轻度认知功能损害的干预效果
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Wei FENG
			        		
			        		;
		        		
		        		
		        		
			        		Chunbo LI
			        		
			        		;
		        		
		        		
		        		
			        		You CHEN
			        		
			        		;
		        		
		        		
		        		
			        		Yan CHENG
			        		
			        		;
		        		
		        		
		        		
			        		Wenyuan WU
			        		
			        		
		        		
		        		
		        		
		        		
		        		
			        		
			        		
		        		
	        		
        		 
        	
        	
        	
        		- Publication Type:Journal Article
 
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Cognition disorders;
			        		
			        		
			        		
				        		Intervention studies;
			        		
			        		
			        		
				        		Cognitive therapy
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			Chinese Journal of Geriatrics
	            		
	            		 2015;34(4):355-358
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	Objective To evaluate the middle and short-term effects of integrative cognitive training on mild cognitive impairments(MCI).Methods All the participants with MCI aged over 70 years were selected from one sub-district of Putuo District,Shanghai and divided into cognitive intervention group (n=46) and control group (n=35).The integrative cognitive training was conducted in 24 sessions for 12 weeks.All subjects were assessed by Neuropsychological Test Battery for Elderly (NTBE) and by a questionnaire of Shanghai Health Survey for the Elderly (VER2006)at baseline,follow-up and one-year follow up phases.Results At baseline phase,semantic relations test in NTBE was better (t=2.13,P=0.037),verbal fluency test (vegetables) in NTBE was worse(t =-2.25,P=0.038) in intervention group than in control group,while there were no significant differences in scores of other neuropsychological tests between intervention group and control group(all P>0.05).At follow up phase,16 subscales in reasoning test of NTBE were improved (t=-2.70,P=0.010)and 2 subscales were declined in cognitive intervention group(all P<0.05).9 subscales in semantic relations test of NTBE (t=-2.27,P=0.013) were improved and 5 subscales were declined in control group (all P< 0.05).Comparison between groups at one year follow-up showed that 5 subscales in reasoning test of NTBE (F=16.80,P=0.000) were better in intervention group than in control group(all P<0.05).General linear model (GLM) with repeated measures at three time points showed that 4 subscales in reasoning test of NTBE had a time-by group interaction (F=5.16,P=0.01).Conclusions Integrative cognitive training can improve cognitive function in patients with mild cognitive impairments,and the validity of reasoning ability can sustain one year.