Uncertainty Analysis of Quercetin Determination in Sicao Tongmai Capsules by HPLC
- VernacularTitle:HPLC测定四草通脉胶囊中槲皮素含量的不确定度评定
- Author:
Juan YANG
;
Li SUN
;
Furong AN
;
Shuping WANG
;
Linghong XIA
;
Houwen LIN
- Publication Type:Journal Article
- Keywords:
Sicao Tongmai capsules;
Uncertainty;
HPLC;
Quercetin;
Sedum sarmentosum
- From:
China Pharmacist
2014;(12):2143-2145
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To analyze the uncertainty of quercetin concentration determination in Sicao Tongmai capsules by HPLC. Methods: The source of uncertainty was confirmed by analyzing the HPLC determination process. The uncertainty components were quantified by statistics, and the extended uncertainty and confidence level were finally obtained. Results: The extended uncertainty of the measurement results was 0. 19 μg · g-1 . Quercetin concentration in Sicao Tongmai capsules was (353. 65 ± 0. 19)μg·g-1 . Conclusion: The uncertainty analysis method is suitable for the standard limit formulation for Sicao Tongmai capsules, and it is important to establish uncertainty analysis methods for traditional Chinese medicines.
