The relationship between serum uric acid and fasting blood glucose in men and women with newly diagnosed type 2 diabetes
10.3760/cma.j.issn.1000-6699.2014.08.006
- VernacularTitle:男女性初发2型糖尿病患者血尿酸与空腹血糖水平的相关性
- Author:
Sha ZHAO
;
Xianghua MA
;
Jie SHEN
;
Xiaona LI
;
Ling YU
;
Weiwei FAN
- Publication Type:Journal Article
- Keywords:
Gender;
Diabetes mellitus,type 2;
Fasting blood glucose;
Serum uric acid
- From:Chinese Journal of Endocrinology and Metabolism
2014;(8):659-662
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationship between serum uric acid and fasting blood glucose ( FBG) in newly-diagnosed type 2 diabetes in regard to different genders. Methods In 282 patients of newly diagnosed type 2 diabetes(208 males and 74 females), detection of serum FBG, uric acid, creatinine, transaminases, blood lipids, etc were determined. FBG<7. 0 mmol/L was found in 118 cases (89 males and 29 females);7. 0 mmol/L≤FBG≤9. 0 mmol/L in 114 cases ( 88 males and 26 females ); FBG>9. 0 mmol/L in 50 cases ( 31 males and 19 females). Results (1)Serum uric acid showed statistically significant difference in regard to sex[Male:(325. 82±92. 26)μmol/L, Female:(292. 26±76. 19)μmol/L, P<0. 01]. (2) FBG and serum uric acid were negatively related(r=-0. 316, P<0. 01). (3) FBG and serum uric acid were negatively related both in male(r=-0. 320, P<0.01)andinfemale(r=-0.291,P<0.05). (4)Multiplestepwiseregressionanalysisshowedthatthethreegroups of FBG and serum uric acid showed regression relationship in male and female patients(P<0. 01). Conclusion With the increased FBG, serum uric acid was decreased in both males and females. Therefore, serum uric acid might serve as a potential biomarker of glucose metabolism.
