Protective effect of the application of Ginkgo-damole in elderly patients with hypertension in total hip arthroplasty
- VernacularTitle:人工全髋关节置换术中应用银杏达莫针对高血压老年患者的保护作用
- Author:
Liang REN
;
Weidong WANG
;
Xuemei WANG
- Publication Type:Journal Article
- Keywords:
total hip replacement;
the old;
hypertension;
Ginkgo-damole
- From:
Chinese Journal of Biochemical Pharmaceutics
2014;(3):81-83
- CountryChina
- Language:Chinese
-
Abstract:
Objective To clarify protective effect of the application of Ginkgo-damole in elderly patients with hypertension in total hip arthroplasty.Methods From January 2012 to December 2013,67 elderly patients with hypertension which should take total hip arthroplasty were divided into observation group and control group.Ginkgo-damole were only used in observation group during the operation.The anesthetic effect and the change of systolic blood pressure(SBP)diastolic blood pressure(DBP),heart rate(HR)and mean arterial pressure(MAP)were observed,postoperative recovery time of consciousness were recorded. Results The level of SBP,DBP,MAP and HR in both group were significantly difference when compared with before anesthesia(P<0.05 ).At the T2-4 time point,the level of SBP,DBP,MAP in observation group were significantly higher than that of control group,the level of HR was significantly lower than the control group,there had significant difference(P<0.05).At the T5 time point,the level of SBP, DBP,MAP and HR in observation group were significantly lower than of control group,there had significant difference between two groups(P<0.05 ).The postoperative recovery time in observation group was(10.41 ±2.35)min,which was lower than that in control group(15.63 ±2.42)min,there had significant difference between two groups(P<0.05 ).Conclusion Ginkgo-damole can effectively relieve the stress reactions caused by anesthesia and total hip arthroplasty,it has good protective effect on elderly patients with hypertension.
