Influence of remifentanil combined with propofol on sober and insulin resistance in patients after esophageal cancer radical surgery

VernacularTitle:瑞芬太尼联合丙泊酚麻醉对食管癌根治术患者术后清醒和胰岛素抵抗的影响
Author: Leqing CAO
Publication Type:Journal Article
Keywords: Esophageal neoplasms; Remifentanil; Propofol; Conscious sedation; Insulin resistance
From: Chinese Journal of Primary Medicine and Pharmacy 2013;20(18):2793-2795
CountryChina
Language:Chinese
Abstract: Objective To study the effect of remifentanil combined with propofol on sober and insulin resistance in patients after esophageal cancer radical surgery.Methods According to the digital table,63 patients with esophageal cancer were randomly divided into the control group (n =32 cases) and the observation group (n =31 cases).The control group were anesthetized through fentanyl plus propofol,while the observation group were anesthetized through remifentanil plus propofol.The level of consciousness and insulin resistance were analyzed.Results 5min after extubation,the OAAS scores of the observation group was (3.8 ± 1.6) points,which was better than that of the control group [(2.9 ± 1.3) points] (t =2.4540,P ＜ 0.05).Compared with preoperation,the insuhn resistance of the two groups were all increased after operation (all P ＜ 0.05).And the insulin resistance in the control group was higher than that in the observation group (P ＜ 0.0 5).Conclusion Remifentanil combined with propofol can improve the level of consciousness and decrease insulin resistance in patients after esophageal cancer radical surgery.