Neuroprotective mechanisms of ischemic preconditioning: caspases and neuronal apoptosis
10.3760/cma.j.issn.1673-4165.2013.03.010
- VernacularTitle:缺血预处理的神经保护机制:胱天蛋白酶与神经元凋亡
- Author:
Pufeng HUANG
;
Chuancheng REN
- Publication Type:Journal Article
- Keywords:
Brain Ischemia;
Ischemic Preconditioning;
Caspases;
Apoptosis
- From:International Journal of Cerebrovascular Diseases
2013;(3):211-215
- CountryChina
- Language:Chinese
-
Abstract:
Ischemic preconditioning may mobilize self-protective mechanisms to induce endogenous neuroprotection through a variety of ways.It has potential clinical application value.Anti-apoptosis is an important part in the protective mechanisms of ischemic preconditioning Caspase family is the key molecule during the apoptotic execution process.It plays an important role in the neuronal apoptosis after cerebral ischemia.This article reviews the ischemic preconditioning-induced neuroprotective mechanisms and the roles of caspase family in neuronal apoptosis after cerebral ischemia.
