The expression of glucose transporters following hypoxia ischemia in the brain
10.3760/cma.j.issn.1673-4408.2012.06.019
- VernacularTitle:葡萄糖转运蛋白在脑缺氧缺血时的表达及调控机制
- Author:
Jie LIU
- Publication Type:Journal Article
- Keywords:
Glucose transporter;
Brain;
Hypoxia ischemia
- From:International Journal of Pediatrics
2012;(6):605-608
- CountryChina
- Language:Chinese
-
Abstract:
Glucose transporter proteins(GLUTs) are the important carriers mediating the transportation of glucose into mammalian cells,there are 13 subtypes expression of GLUT,each subtypes express parts and function is different.The expression of Glucose transporters are increased following hypoxia ischemia in the brain,in order to promote the glucose transshi-pment in the brain,adapt to the needs of increasing anaerobic glycolysis.It has an important role in maintaining enough energy supplement for the brain,delaying a cascade reaction of cerebral energy failure.This article is a review about the features of GLUT,dynamic change and significance of brain after hypoxic-ischemia.
