Resveratrol neuroprotection in cerebral ischemia
10.3760/cma.j.issn.1673-4165.2012.07.012
- VernacularTitle:白藜芦醇在脑缺血中的神经保护作用
- Author:
Yongjiu WANG
;
Zhenqing GONG
;
Yan CHENG
- Publication Type:Journal Article
- Keywords:
Resveratrol;
Stilbenes;
Brain Ischemia;
Ischemic Preconditioning;
Neuroprotective Agents;
Antioxidants
- From:
International Journal of Cerebrovascular Diseases
2012;20(7):542-546
- CountryChina
- Language:Chinese
-
Abstract:
Resveratrol is a polyphenolic compounds in many plants.It has many effects inchuding antioxidation,anti-inflammation,inhibiting apoptosis,and scavenging free radicals.Resveratrol preconditioning has neuroprotective effect in ischemia-reperfusion in rats by activating silent information regulator 2 homolog 1.This effect is similar to brain ischemic preconditioning.In addition,resveratrol can also attenuate the brain infraction volume of cerebral ischemia/reperfusion in mice and improve neurological function.This article reviews the neuroprotective effect of resveratrol and its mechanisms in cerebral ischemia.
