Effect of mitiglinide calcium on fasting plasma fibroblast growth factor-21 level in patients with newly diagnosed type 2 diabetes mellitus
10.3760/cma.j.issn.1000-6699.2012.02.014
- VernacularTitle:米格列奈钙对初诊2型糖尿病患者血浆成纤维细胞生长因子21水平的影响
- Author:
Yingying FAN
;
Gangyi YANG
;
Ling LI
;
Zhiyong LI
;
Yong LIAO
;
Chunrui CHENG
;
Shiguo TANG
;
Shengbing LI
;
Na LI
;
Yi WANG
- Publication Type:Journal Article
- Keywords:
Mitiglinide calcium;
Diabetes mellitus,type 2;
Fibroblast growth factor-21
- From:Chinese Journal of Endocrinology and Metabolism
2012;28(2):143-145
- CountryChina
- Language:Chinese
-
Abstract:
Eighty-two newly-diagnosed type 2 diabetic patients with poor glycemic control were treated by mitiglinide calcium for 16 weeks.Plasma fibroblast growth factor-21 ( FGF-21 ) level were evaluated.The relationship of plasma FGF-21 levels with body mass index,body fat,waist-to-hip ratio,lipid,blood glucose,HbA1c,and free fatty-acid were analyzed.Plasma FGF-21 was decreased significantly by treatment with mitiglinide calcium in type 2 diabetic patients,and it may play a role in the pathogenesis of type 2 diabetes mellitus.
