Long-term outcome of urethral reconstruction using colonic mucosa graft for the treatment of longsegment, complex urethral strictures
10.3760/cma.j.issn.1000-6702.2011.11.005
- VernacularTitle:结肠黏膜尿道成形治疗复杂性超长段尿道狭窄的长期疗效
- Author:
Yuemin XU
;
Yong QIAO
;
Yinglong SA
;
Qiang FU
;
Jiong ZHANG
;
Lujie SONG
- Publication Type:Journal Article
- Keywords:
Transplants;
Urethral stricture;
Urethroplasty;
Colonic mucosa;
Long-term
- From:
Chinese Journal of Urology
2011;32(11):736-739
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo investigate the long-term outcome of urethral reconstruction using colonic mucosa grafts for the treatment of long-segment,complex urethral strictures and to identify clinical factors that impact long-term outcomes. MethodsForty-six patients underwent colonic mucosal graft urethroplasty from October 2000 to September 2009 were retrospectively reviewed.The mean age was 39 years ( range,17 -70).The patients underwent an average of 2.7 prior unsuccessful repairs and the mean length of urethral strictures was 15.2 cm (range,10.0 to 20.0).The voiding status of all patients was evaluated postoperatively.Some of the paitents underwent uroflowmetry.urethrography and urethroscopy.Successful repair was defined as voiding well with urinary peak flow greater than 15 ml/s without the need for any post-operative procedures,such as dilatation. ResultsUrethral reconstruction was done with colonic mucosa grafts 11.0 -21.0 cm long (mean 15.4).One patient was lost to follow-up.Mean follow-up in the remaining cases was 62 months ( range 20 - 120 ).Complications related to urethroplasty developed in four patients (8.9％).Of these patients,meatal stenosis developed in three patients at 3,8 and 24 months respectively.Anastomotic site stricture occurred at the neourethra and proximal urethra in one patient at 29 months.In another two patients,recurrent strictures unrelated to urethroplasty were found. ConclusionsColonic mucosa graft urethroplasty could be an effective technique for the treatment of complex urethral strictures or panurethral strictures.The factors that impact long-term outcomes are meatal stenosis and stenosis at the anastomosis.
