Abdominal radical surgery and regional lymph node dissection for treatment of renal carcinoma (report of 136 cases)
10.3760/cma.j.issn.1000-6702.2011.05.005
- VernacularTitle:经腹肾癌根治术并系统性淋巴结清扫治疗肾细胞癌临床分析(附136例报告)
- Author:
Zecheng NI
;
Yu ZHANG
;
Lanting HU
;
Shenjun WANG
;
Kebaier AI
;
Feng GUO
;
Qing WANG
- Publication Type:Journal Article
- Keywords:
Carcinoma,renal cell;
Nephreetomy;
Lymphadenectomy
- From:
Chinese Journal of Urology
2011;32(5):307-309
- CountryChina
- Language:Chinese
-
Abstract:
Objective To assess the safety and efficacy of abdominal radical nephrectomy and systematic lymph node dissection for treatment of renal carcinoma. Methods A total of 136 patients underwent radical nephrectomy and regional clearance of lymph nodes from July 2004 to June 2008.There were 92 males and 44 females in the study group.Ages ranged from 23 to 81 years,with a mean age of 54 years.The mean tumor diameter was 55 mm (range,15-170 mm).The tumor size detected by CT and MRI was consistent with that detected by B-ultrasound,98 were stage Ⅰ,13stage Ⅱ,12 stage Ⅲ,and 2 stage Ⅳ. Results All 136 cases underwent radical nephrectomy with retroperitoneal lymphadenectomy.All operations were successful without any major complication.The operative time was 90 to 180 min,with an average of 120 min,and blood loss was 20-400 ml,with an average of 50 ml.The pathological diagnoses were as follows: renal cell carcinoma 123 cases (90%), papillary renal cell carcinoma six cases(4%),chromophobic two cases(1.4%),oncocytoma two cases(1.4%),collecting duct two(1.4%),and others three cases(2.2%).Eight cases reported positive lymph nodes.Of the 136 cases,92 cases were T1 N0 M0,11 were T2 N0 M0,10 were T3 N0 M0,eight were T3 N1 M0 and two were T1 N0 M1.Ninety-five cases (70%) were followed-up at six to 40 months (mean,20 months).The one year and three year survival rates were 96% (91/95) and 86% (82/95),respectively.Conclusions Radical nephrectomy with systematic lymph dissection has advantages of accurate staging,effective resecting of renal tumors and preventing recurrence.Radical nephrectomy is an effective method for the treatment of renal carcinoma.
