The level of endogenous secretory receptor for advanced glycation end-products in type 2 diabetes patients is associated with carotid intima-media thickness
10.3760/cma.j.issn.1000-6699.2011.04.013
- VernacularTitle:内源分泌型晚期糖化终末产物受体与2型糖尿病颈动脉内膜中层厚度相关
- Author:
Xiahong LIN
;
Xiaoyu CHEN
;
Xisheng LI
;
Huili LIN
;
Ziyang HUANG
;
Jingxiong ZHOU
;
Bo HANG
;
Ruhai LIN
;
Xiaohong WU
- Publication Type:Journal Article
- Keywords:
Diabetes mellitus;
Endogenous secretion receptor for advanced glycation end-products;
Carotid intima-media thickness;
Arteriosclerosis
- From:
Chinese Journal of Endocrinology and Metabolism
2011;27(4):320-321
- CountryChina
- Language:Chinese
-
Abstract:
The carotid initima-media thickness(CIMT)in 78 cases of type 2 diabetic patients was measured.The level of plasma endogenous secretion receptor for advanced glycation end-products(esRAGE)in patients with normal CIMT was higher than those with chickened CIMT[(0.257 3±0.165 6 vs 0.155 4±0.0701)μg/L,P<0.01].esRAGE was negatively associated with CIMT(r=-0.247,P<0.05).Logistic regression analysis showed that CIMT was negatively associated with esRAGE and hish density lipoprotein cholesterol,but was positively associated with age.
