Analysis of 50 Cases of Severe Liver Function Damage Induced by Antituberculotics
- VernacularTitle:抗结核药物致严重肝功能损害50例分析
- Author:
Jinhai FENG
;
Tongzhu WU
- Publication Type:Journal Article
- From:
China Pharmacy
2001;12(3):168-169
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE： To discuss the severe liver function damage induced by antituberculostics.METHODS： The severe liver function damage induced by antituberculotis was analyzed in 50 patients admitted into this hospital from January 1995 to January 2000.RESULTS： Sever liver function damage was related to the following factors:(1)history of liver diseases;(2)aged patient and malnutritional patient;(3)chronic alcoholism;(4)combined use of isoniazid,rifampin with other drugs;(5)hepatic dysfunction before treatment.CONCLUSION： The abovementioned factors should be under consideration in choice of antituberculotics.
