Angiotensin Ⅱ Receptor Blockers and Neuroprotection
- VernacularTitle:血管紧张素Ⅱ受体阻滞剂与神经保护
- Author:
Zeng ZHOU
;
Zhaohu CHU
- Publication Type:Journal Article
- Keywords:
angiotensinⅡreceptor blocker;
neuroprotection;
angiotensin Ⅱ receptor
- From:International Journal of Cerebrovascular Diseases
2008;16(3):193-196
- CountryChina
- Language:Chinese
-
Abstract:
Angiotensin Ⅱ receptor blockers(ARBs)decrease blood pressure,reverse vascular remodeling,and activate angiotensinⅡsubtype 2(AT2)receptors in order to improve the levels of angiotensinⅡ(AngⅡ),dilate blood vessels,protect against proliferation,and regulate lipid by blocking angiotcnsinⅡtype 1(AT1)receptors.Further understanding the action mech-anism of ARB in neuroprotection may provide a new idea for the treatment of ischemic stroke in clinical practice.
