Clinical and neuroimaging futures of chorea due to nonketotic hyperglycemia:7 cases report
- VernacularTitle:非酮症性高血糖舞蹈症七例临床及神经影像学特点
- Author:
Xuewu LIU
;
Guoqing DONG
;
Lijun SU
;
Xiuhe ZHAO
;
Wei WU
;
Lili CAO
;
Shuhua WANG
;
Shengjun WANG
;
Zhaofu CHI
- Publication Type:Journal Article
- Keywords:
Hyperglycemia;
Chorea;
Tomography,X-ray computed;
Magnetic resonance imaging
- From:Chinese Journal of Neurology
2008;41(6):404-408
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical and neuroimaging futures of chorea due to nonketotic hyperglycemia.Methods Seven cases of chorea due to nonketotic hyperglycemia were clinically examined and underwent brain CT and MRI as well.Results Investigations revealed uncontrolled diabetes with absent ketones of 7 cases.They all presented with sudden onset hemiachorea or bilateral chorea or generalized chorea.The CT scan of brain could find abnormal lesions in our cases.Hyperintense lesions in the basal ganglia,on T1 WI of MRI were demonstrated in our study.Pure drugs was unable to control chorea.The symptoms of chorea and neuroimaging lesions were normal after the hyperglycemia being controlled.Conclusions Chorea caused by nonketotic hyperglycemia is mainly found in aged people with diabetes mellitus in a mechanism of causing striatal neuronal dysfunction,presenting charicristic CT scan or MRI of brain.Chorea should be considered potentially reversible when associated with nonketotic hyperglycemia,for rapid detection and early correction of hyperglycemia could lead to complete recovery of these involuntary movements.
