Effects of obesity on insulin resistance, β-cell function and serum high-sensitivity C-reactive protein level in first-degree relatives of type 2 diabetic patients
- VernacularTitle:肥胖对2型糖尿病一级亲属胰岛素抵抗、β细胞功能和超敏C反应蛋白水平的影响
- Author:
Xiaolin CHEN
;
Jing LI
;
Zhongyuan WEN
;
Yonglin SUN
;
Ying WANG
;
Xiaoli CAI
;
Bo ZHOU
;
Zhenjin LI
- Publication Type:Journal Article
- Keywords:
Obesity;
Diabetes mellitus,type 2;
First-degree relatives;
Insulin resistance;
C-reactive protein
- From:Chinese Journal of Endocrinology and Metabolism
2008;24(5):521-522
- CountryChina
- Language:Chinese
-
Abstract:
Insulin sensitivity,β-cell function and serum high-sensitivity C-reactive protein (hs-CRP)levels were observed in obese and non-obese normoglycemic first-degree relatives of type 2 diabetic patients (FDR). The results showed that there existed insulin resistance,β-cell dysfunction and increased serum hs-CRP level in obese FDR of type 2 diabetic patients. Moreover, insulin resistance and increased CRP level were positively related to waist circumference.
