Effect Donglian Capsule on Nonenzymatic Protein Glycation in Diabetes Melitus Rat
- VernacularTitle:冬连胶囊对糖尿病大鼠蛋白非酶糖基化的影响
- Author:
Qiwei SUN
;
Pu GAO
;
Jiangang LIU
- Publication Type:Journal Article
- Keywords:
Donglian capsule;
Glycosylation serum protein;
Aldose reductase;
Nonenzymatic protein glycation
- From:
International Journal of Traditional Chinese Medicine
2008;30(6):407-408
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of Donglian capsule on nonenzymadc protein glycation.Methods An animal model of DM was established by injecting a little dosage of STZ in high fat-fed rats.When the models were established successfully,corresponding medicines were supplied for 12 weeks and then the blood glucose,glycosylation serum protein(GSP)and aldose reductase(AR)in rats semm were measured.Results Comparing with the model group,the levels of blood glucose,GSP and AR in Metformin Hydrochloride tablets group and Chinese medicine group were decreased markedly (P＜0.05).Conclusion Donglian capsule Can restrain nonenzymatic protein glycation and so thus prevent and treat DM.
