Relationship between plasma level of endogenous secretory receptor of advanced glycation end products and oxidative stress in diabetic patients with hypertension
10.3760/cma.j.issn.1000-6699.2009.02.014
- VernacularTitle:2型糖尿病高血压患者血浆内源性分泌型晚期糖基化终末产物受体和氧化应激的关系
- Author:
Xingping SHEN
;
Senbiao ZOU
;
Haovjie WU
;
Yan ZHANG
- Publication Type:Journal Article
- Keywords:
Diabetes mellitus,type 2;
Advanced glycation end product receptor;
Oxidative stress
- From:
Chinese Journal of Endocrinology and Metabolism
2009;25(2):174-176
- CountryChina
- Language:Chinese
-
Abstract:
The relationship between plasma level of endogenous secretory receptor of advanced glyeation end products(esRAGE)and oxidative stress in diabetic patients with hypertension was investigated.The results showed that there was significant negative correlation between esRAGE and body mass index(BMI,r=-0.33), diastolic blood pressure(DBP,r=-O.38)and oxidative stress(all P<0.05).The levels of plasma esRAGE decreased significantly in diabetic patients with hypertension.BMI,DBP and oxidative stress may participate in determinining the esRAGE level in diabetic patients complicated with hypertension.