Association of PPARγ2 gene C1431T polymorphism to serum adipokines in women with poly cystic ovary syndrome
10.3760/cma.J.issn.1000-6699.2009.05.007
- VernacularTitle:多囊卵巢综合征患者PPARγ2基因C1431T多态性与血脂肪因子水平变化相关
- Author:
Tao TAO
;
Wei LIU
;
Xiangyang XUE
;
Shengxian LI
;
Jiejin YANG
;
Xiuying MAO
;
Fengying LI
- Publication Type:Journal Article
- Keywords:
Polycystic ovary syndrome;
PPARγ;
Polymorphism,restriction fragment length;
Adiponectin
- From:
Chinese Journal of Endocrinology and Metabolism
2010;26(5):370-371
- CountryChina
- Language:Chinese
-
Abstract:
PPARγ2 gene C1431T polymorphism was assayed by PCR-RFLP in 200 polycystic ovary syndrome( PCOS)patients and 150 normal subjects. Serum adiponectin and leptin levels were determined by ELISA method. Polymorphism of the site might be associated with serum leptin and adiponectin concentrations and thiazolidinedione treatment in women with PCOS ( P<0.05 or P<0.01).
