Clinical analysis of mucinous tubular and spindle cell carcinoma of the kidney
10.3760/cma.j.issn.1000-6702.2010.10.008
- VernacularTitle:肾黏液小管状和梭形细胞癌的临床特点分析
- Author:
Xingcheng WU
;
Hanzhong LI
;
Zhigang JI
;
Ruiqiang ZHANG
;
Weigang YAN
;
Ruie FENG
;
Dachun ZHAO
- Publication Type:Journal Article
- Keywords:
Kidney neoplasms;
Mucinous tubular and spindle cell carcinoma;
Diagnosis;
Treatment;
Prognosis
- From:
Chinese Journal of Urology
2010;31(10):675-678
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical features, treatment and prognosis of mucinous tubular and spindle cell carcinoma of the kidney. Methods Patient 1, a 42-year-old woman presented with space-occupying lesion of the lower pole of the left kidney with no symptoms in physical examination for 1 week. CT revealed a low-enhanced tumor located in the lower pole of the left kidney in cT1b N0M0. Radical left nephrectomy was performed. Patient 2, a 76-year-old woman presented with space-occupying lesion of the middle of the left kidney with no symptoms in physical examination for 10 d. CT revealed a low-enhanced tumor located in the middle of the left kidney in cT1b N0 M0. Laparoscopic radical left nephrectomy was performed. The patient received adjuvant treatment with IL-2 and interferon-α 3 months after nephrectomy. Patient 3, a 50-year-old woman presented with lumbago for 3 months. CT revealed a low-enhanced tumor located in the right kidney in cT2 N0 M0. Radical right nephrectomy was performed. The patient received adjuvant treatment with IL-2 and interferon-α 3months after nephrectomy. Patient 4, a 60-year-old woman presented with lumbago and hematuria for 15 d. CT revealed a low-enhanced tumor located in the lower pole of the left kidney in cT1a N0M0.Radical left nephrectomy was performed. Results Histological examination of the tumors showed that they consisted of spindle cells arranged in tubular and trabecular patterns embedded in a myxoid stroma. Pathologic diagnosis of all 4 patients were MTSCCa. There was no evidence of recurrence in all patients for 9- 46 months. Conclusions MTSCCa is a rare low-grade renal cell carcinoma.There is a female predominance. Early surgical excision is the best treatment and the prognosis is relatively good.
