Anti-Allergic ‘Benifuuki’ Green Tea
10.1625/jcam.3.53
- VernacularTitle:抗アレルギー効果のある茶葉成分
- Author:
Mari MAEDA-YAMAMOTO
- Publication Type:Journal Article
- Keywords:
‘Benifuuki’ green tea;
epigallocatechin-3-O-(3-O-methyll)gallate (EGCG3″Me);
Anti-allergic action;
Inhibition of mast cell activation
- From:Japanese Journal of Complementary and Alternative Medicine
2006;3(2):53-60
- CountryJapan
- Language:Japanese
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Abstract:
We have reported that O-methylated EGCG (epigallocatechin-3-O-(3-O-methyl)gallate (EGCG3″Me) had 2.5-fold anti-allergic action compared with EGCG (epigallocatechin gallate), and that the tea (Camellia sinensis L.) cultivar ‘Benifuuki’ was rich in EGCG3″Me. The EGCG3″Me content was high and caffeine content decreased in fully-matured tea leaves in second or third crop season, and EGCG3″Me was disappeared under black tea manufacturing process. ‘Benifuuki’ is a cultivar with strong resistance for diseases, strong vigor of plant, many yield and excellent fragrance. The EGCG3″Me strongly inhibited mast cell activation through the prevention of tyrosine phosphorylation (Lyn, Syk and Btk) of cellular protein, the phosphorylation of myosin light chain and the expression of Fcepsolon RI, and histamine/leukotrienes release. Furthermore, over one consecutive month intake of ‘Benifuuki’ green tea was useful for reduction of some symptoms derived from Japanese cedar pollinosis, and did not affect any normal immune response in the subjects with Japanese cedar-pollinosis. So, in cooperation with food companies, we developed PET beverage and sweet using ‘Benifuuki’ green tea.
