Studies on the Hepatoprotective Activity of Oleanolic Acid from Wedelia calendulacea Less
- Author:
Nguyen Thi Xuan Hoa
- Publication Type:Journal Article
- Keywords:
Wedelia calendulacea Less
- MeSH:
Plants;
Plants, Medicinal;
Liver Diseases;
liver;
drugs;
Oleanolic Acid
- From:Journal of Medicinal Materials - Hanoi
2003;8(5):146-149
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
The Wedelia calendulacea Less. in Van Dien area, Ha Noi, rats of the body weight of 20-22g were divided into 3 groups. In order to use Wedelia calendulacea Less. in treating liver diseases, fractions from the plant have been studied pharmacologically. This paper presents the method of extraction of oleanolic acid and results of its anti-oxidative effect. The studies have revealed that amount of liver MDA of the treated mice decreased by 44.8%, and that of serum GPT decreased by 26.3%. These results show that oleanolic acid do take part in the hepatoprotective activity of the plant
