Evaluation of hepatoprotective effect of wedelia calendulacea lees
- Author:
Nguyen Thi Xuan Hoa
- Publication Type:Journal Article
- Keywords:
Wedelia calendulacea lees, hepatoprotective
- MeSH:
Medicine, Traditional;
Therapeutics;
Gastroenterology;
drugs
- From:Journal of Medicinal Materials - Hanoi
2003;8(2):91-94
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
The 1:1 fluid extract of Wedelia calendulacea Less. aerial part was used for the evaluation of the plant hepatoprotective effect. The results of the pharmacological studies included: (1) Oxidative activity: 83.1% (in vitro), (2) Decrease of malonyl dialdehyde in mouse liver: 25.1%, (3) Decrease of the serum glutamate pyruvic transaminase level: 34.1%, (4) Decrease of the concentration of bilirubin in mouse serum: 10.4%, (5) Increase of the bile flow in mice: 88.8%. Conclusion: W. calendulacea had a good hepatoprotective effect in mouse model.
