Anti-biofilm effects of Zn lactate·3H₂O and SnF₂ on Pseudomonas aeruginosa, Acinetobacter baumannii and Streptococcus mutans.

Author: Shan YU ¹ ; Miaokun ZHANG ² ; Luyan MA ¹
Author Information

1. Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.
2. University of Chinese Academy of Sciences, Beijing 100049, China.
Publication Type:Journal Article
Keywords: Acinetobacter baumannii; Pseudomonas aeruginosa; SnF₂; Streptococcus mutans; Zn lactate·3H₂O; biofilm
From: Chinese Journal of Biotechnology 2017;33(9):1478-1488
CountryChina
Language:Chinese
Abstract: Zn lactate and SnF₂ were used as active compounds in the dentifrice. Here, their anti-biofilm effects were evaluated on Pseudomonas aeruginosa, Acinetobacter baumannii and Streptococcus mutans. The biofilm prevention/dispersal assay of P. aeruginosa PAO1 demonstrated that Zn lactate and SnF₂ can inhibit biofilm formation independently or by combined treatment. Zn lactate disrupted extracellular polysaccharides matrix formation and SnF₂ reduced the biomass of biofilm. Most importantly, the combination of Zn lactate and SnF₂ thoroughly abolished the biofilm formation of all three strains.