Development of Upgraded Cortical Impact Model(Part I: Mechanics).
- Author:
Seok Min CHOI
1
;
Jong Sik SUK
;
Jeong Taik KWON
;
Byung Kook MIN
;
Young Baeg KIM
;
Sung Nam HWANG
;
Duck Young CHOI
;
Jae Hyun KIM
;
Sung Min LEE
;
Yun Yong EARMME
Author Information
1. Department of Neurosurgery, Chung-Ang University School of Medicine, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Upgraded cortical impact model;
Impact velocity;
Pneumatic cylinder
- MeSH:
Animal Experimentation;
Animals;
Craniocerebral Trauma
- From:Journal of Korean Neurosurgical Society
2002;32(1):29-34
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVE: Head trauma model is important and essential to development of new therapeutic modality. We present a upgraded head trauma model for experimental animals. METHODS: Using pneumatic cylinder, solenoid valve, linear variable differential transformer(LVDT) and load cell, we developed "Chung-Ang University Hospital Model 1.0(CAUH-1)" based on controlled cortical impact model. RESULTS: Changing pressure, impact velocity could be controlled up to 4m/sec. Using solenoid valve, we could control dwell time precisely. Real time impact force could be measured with load cell. CONCLUSION: Controlling dwell time, impact velocity, depth of deformation, this model would reproduce variable degrees of head injury. This model is so precise and versatile that it would be useful in diverse animal experimental researches.
