Effects of the extract from bergamot and boxthorn on the delay of skin aging and hair growth in mice.
- Author:
Lin-xiang SHAO
1
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Citrus; chemistry; Collagen; metabolism; Drugs, Chinese Herbal; isolation & purification; pharmacology; Female; Hair; growth & development; Lycium; chemistry; Male; Malondialdehyde; metabolism; Mice; Mice, Inbred ICR; Plants, Medicinal; chemistry; Random Allocation; Skin; metabolism; Skin Aging; drug effects; Superoxide Dismutase; metabolism
- From: China Journal of Chinese Materia Medica 2003;28(8):766-769
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the effects of the extract from bergamot and boxthorn on the skin and the hair growth in mice.
METHODThe skin on the back of mice was shaved topically and smeared with bergamot and boxthorn extract for 42 days. Then the activity of superoxide dismutase (SOD) and the content of malondialdehyde (MDA) and collagen in the mice were measured. The growth of hair was also observed.
RESULTCompared with control group, the extract from bergamot and boxthorn obviously increased the activity of superoxide dismutase (P < 0.05) and the content of collagen (P < 0.001), and decreased the content of malondialdehyde (P < 0.05) in the skin of mice. It also significantly promoted the growth of hair (P < 0.001).
CONCLUSIONThe extract from bergamot and boxthorn plays an active role in skin and the promotion of hair growth.
