Treatment of Hodgkin\u2019s disease with ABVD followed by low-dose involved field of radiotherapy: analysis of efficacy
- Author:
Mai Tuyet Nguyen
;
Duc Ba Nguyen
- Publication Type:Journal Article
- Keywords:
Hodgkin;
complete response (CR);
relapse-free survival (RFS);
overall survival (OS)
- MeSH:
Hodgkin Disease/ radiotherapy;
- From:Journal of Medical Research
2007;47(1):60-64
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Background: Treatment of Hodgkin\u2019s disease with ABVD followed by low-dose involved field of radiotherapy is currently considered the standard of care. Objectives: This study was evaluated the efficacy and some pronogstic factors. Subjects and method: 103 consecutive patients with newly diagnosed HD\ufffd?disease treated with combination CT and RT at K-hospital between 10/2001 \ufffd?3/2005 were eligible. The end points of the study were complete response (CR), relapse-free survival (RFS), overall survival (OS). Tests were used for analysis: chi-square test, Kaplan-Meier method... Results: 103 patients (100%) achieved a CR. The RFS and OS rate at 5 years were 64,6% and 91,7%. Pronogstic factors are sex, anemia, B symtom, liver lesion. Conclusion: Treatment plan has brought the most effective so far. Liver damage is a bad influence markedly the survival time.
