Magnetic activated cell sorting and its application in the studies of male infertility.
- Author:
Xue-lian DENG
1
;
Fa-quan LIN
Author Information
1. Department of Laboratory Medicine, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi 530021, China.
- Publication Type:Journal Article
- MeSH:
Cell Separation;
methods;
Flow Cytometry;
Humans;
Infertility, Male;
Magnetics;
Male;
Semen Analysis
- From:
National Journal of Andrology
2012;18(1):70-73
- CountryChina
- Language:Chinese
-
Abstract:
Magnetic activated cell sorting (MACS) is considered as a flexible, fast, specific and simple cell sorting system that can separate target cells effectively according to specific markers on the cell surface, for which it has won a wide clinical application. MACS offers a new platform for male infertility research, as well as a novel idea for applying this technology in the optimization of semen quality and the isolation of germ cells. This article briefly introduces the basic principles of MACS, and summaries its present and potential clinical application in male infertility research, as in spermatozoa selection and cryopreservation, and the isolation of spermatogonial stem cells and germ cells.
