Mammary fibroadenoma in a lamb.
- Author:
M Yavuz GULBAHAR
1
;
Tolga GUVENC
;
Murat YARIM
;
Yonca B KABAK
;
Yuksel SOZGEN
Author Information
- Publication Type:Case Report
- Keywords: fibroadenoma; lamb; mammary gland; ovine; tumor
- MeSH: Animals; Female; Fibroadenoma/pathology/*veterinary; Keratins/metabolism; Mammary Glands, Animal/*pathology; Mammary Neoplasms, Animal/*pathology; Sheep; Sheep Diseases/*pathology; Vimentin/metabolism
- From:Journal of Veterinary Science 2007;8(4):423-425
- CountryRepublic of Korea
- Language:English
- Abstract: A fibroadenoma was diagnosed in the left udder of a 3-month-old female Chios lamb. No recurrence was observed after surgery. Grossly, the tumor had a whitishgray lobular appearance, and the lobules were interlaced with thin septa. Microscopically, the tumor was composed of proliferating fibroepithelial tissue, including differentiated ducts lined by whorls and interlacing bundles of abundant loose fibrovascular stroma. Immunohistochemistry revealed the ductal epithelium to be positive for pancytokeratin (AE1/AE3) and loose fibrovascular stroma was positive for vimentin and basal cells covering the ductal epithelium of alpha-smooth-muscle actin. Immunostaining for the estrogen and progesterone receptors was negative. A diagnosis of mammary fibroadenoma was made based on the histological and immunohistochemical findings.
