Ampullary Carcinoid Tumor.
- Author:
Dong Sun SHIN
1
;
Dae Young KANG
;
In Sang SONG
Author Information
1. Department of Surgery, College of Medicine, Chungnam National University, Korea. songis@cnuh.co.kr
- Publication Type:Case Report
- Keywords:
Ampullar of Vater;
Carcinoid;
Endocrine tumor
- MeSH:
Aged;
Ampulla of Vater;
Bile;
Carcinoid Tumor*;
Common Bile Duct;
Cytoplasm;
Drainage;
Eosinophils;
Gastrointestinal Tract;
Humans;
Jaundice;
Pancreaticoduodenectomy;
Phosphopyruvate Hydratase;
Synaptophysin
- From:Korean Journal of Hepato-Biliary-Pancreatic Surgery
2006;10(4):34-37
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The ampullary carcinoid tumor is a rare lesion accounting for less than 0.3% of all carcinoid tumors of the gastrointestinal tract. We recently experienced a case of an ampullary carcinoid tumor at our institution. A 70-year-old man was admitted to our hospital on January 2006 for right upper quadrant pain with jaundice. He underwent a pyloruspreserving pancreaticoduodenectomy for an ampullary carcinoid tumor. Abdominal computed tomography showed an oval shaped mass at the ampulla of Vater with abrupt obstruction of the distal end of the common bile duct. The patient underwent a percutaneous transhepatic bile drainage for a cholangiogram, in which was noted a filling defect with a smooth margin at the ampullary portion. During surgery, a firm, grayish-pink, and fairly well circumscribed tumor measuring 2.5 cm was found in the ampulla of Vater. Histopathologically, the tumor with invasion to the muscular layers consisted of cells with an eosinophillic cytoplasm and uniform, oval hyperchromatic nuclei. Immunohistochemical staining of the tumor was positive for chromogranin, synaptophysin and neuron-specific enolase. The patient had an unremarkable hospital course. Carcinoids of the ampulla of Vater are very rare. Only 105 cases have been reported in the literature, most as single case reports. We report here a case of an ampullary carcinoid tumor with a discussion based on the literature.
