A Case of Acute Hepatic Failure due to Acetaminophen Overdose Treated with Molecular Adsorbents Recirculating System(R).
- Author:
Byung Keun YANG
1
;
Je Sung YOU
;
Young Seon JOO
;
Sung Phil CHUNG
;
Hahn Schick LEE
Author Information
1. Department of Emergency Medicine, Yonsei University College of Medicine, Seoul, Korea. emstar@yuhs.ac
- Publication Type:Case Report
- Keywords:
Poisoning;
Acetaminophen;
Liver failure
- MeSH:
Acetaminophen*;
Cysteine;
Dialysis;
Eating;
Humans;
Liver Failure;
Liver Failure, Acute*;
Mars;
Poisoning
- From:Journal of The Korean Society of Clinical Toxicology
2014;12(1):31-34
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We report on a patient who developed acute hepatic failure despite intravenous N-acetyl cysteine therapy who was treated with the Molecular Adsorbents Recirculating System (MARS). She presented 20 hours after the ingestion of 13 g of acetaminophen. The MARS is based on albumin dialysis principle which can be applied for patients with acute poisoning from drugs that have high protein-binding capacity because of its ability to selectively remove from circulation protein-bound toxins. The clinical toxicologist should be consider this technology when treating patients with hepatic failure following acetaminophen poisoning.
