Paranasal Aspergillosis in Patients Prior to Liver Transplantation.
10.4285/jkstn.2011.25.4.245
- Author:
Bum Gyoon KIM
1
;
Youngnam ROH
;
Hyunghwan MOON
;
Tae Seok KIM
;
Sanghoon LEE
;
Sanghyun SONG
;
Milljae SHIN
;
Jong Man KIM
;
Choon Hyuck KWON
;
Sung Joo KIM
;
Jae Won JOH
;
Suk Koo LEE
Author Information
1. Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. jw.joh@samsung.com
- Publication Type:Original Article
- Keywords:
Fungal infection;
Liver transplantation;
Aspergillosis;
Functional endoscopic sinus surgery
- MeSH:
Aspergillosis;
Carcinoma, Hepatocellular;
Hepatitis B virus;
Humans;
Liver;
Liver Transplantation;
Male;
Prognosis;
Recurrence;
Transplants
- From:The Journal of the Korean Society for Transplantation
2011;25(4):245-248
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Aspergillosis infection is associated with high morbidity and mortality in liver transplant recipients. This study investigated the prognosis of liver transplant recipients with a pre-operative treatment for paranasal aspergillosis. METHODS: We collected data from 979 cases of patients who underwent liver transplants at the Samsung Medical Center from May 1996 to Feburary 2010. RESULTS: Eight patients were diagnosed with paranasal aspergillosis after functional endoscopic sinus surgery (FESS), before liver transplantation. In these 8 patients, 7 (87.5%) were male, with a mean age of 55 years. All patients had a hepatitis B virus infection, and 6 patients had hepatocellular carcinoma. The mean days from FESS to liver transplantation was 31 (range, 12~47 days) and anti-fungal agents were not used during these periods. All 8 patients were free from a recurrence of aspergillosis after liver transplantation. CONCLUSIONS: Surgical treatment for paranasal aspergillosis in patients prior to liver transplantation does not induce aspergillosis infection after transplantation.
