Epidemiology, Risk Factors, and Clinical Features of Intracerebral Hemorrhage: An Update.
- Author:
Sang Joon AN
1
;
Tae Jung KIM
;
Byung Woo YOON
Author Information
- Publication Type:Review
- Keywords: Cerebral hemorrhage; Epidemiology; Incidence; Risk factors; Neurologic manifestations
- MeSH: Aged; Alcohol Drinking; Anticoagulants; Asian Continental Ancestry Group; Atrial Fibrillation; Cerebral Amyloid Angiopathy; Cerebral Hemorrhage*; Cognition Disorders; Epidemiology*; Hematoma; Hemorrhage; Humans; Hypertension; Incidence; Male; Mortality; Neurologic Manifestations; Renal Insufficiency, Chronic; Risk Factors*; Smoke; Smoking; Stroke; Survivors; Warfarin
- From:Journal of Stroke 2017;19(1):3-10
- CountryRepublic of Korea
- Language:English
- Abstract: Intracerebral hemorrhage (ICH) is the second most common subtype of stroke and a critical disease usually leading to severe disability or death. ICH is more common in Asians, advanced age, male sex, and low- and middle-income countries. The case fatality rate of ICH is high (40% at 1 month and 54% at 1 year), and only 12% to 39% of survivors can achieve long-term functional independence. Risk factors of ICH are hypertension, current smoking, excessive alcohol consumption, hypocholesterolemia, and drugs. Old age, male sex, Asian ethnicity, chronic kidney disease, cerebral amyloid angiopathy (CAA), and cerebral microbleeds (CMBs) increase the risk of ICH. Clinical presentation varies according to the size and location of hematoma, and intraventricular extension of hemorrhage. Patients with CAA-related ICH frequently have concomitant cognitive impairment. Anticoagulation related ICH is increasing recently as the elderly population who have atrial fibrillation is increasing. As non-vitamin K antagonist oral anticoagulants (NOACs) are currently replacing warfarin, management of NOAC-associated ICH has become an emerging issue.
