Long-term efficacy of transmural and transpapillary drainage for disconnected pancreatic duct syndrome
10.3760/cma.j.cn321463-20240118-00035
- VernacularTitle:透壁穿刺与经乳头引流对胰管断裂综合征的远期疗效观察
- Author:
Tszyau CHEUNG
1
;
Wen SHI
;
Shengyu ZHANG
;
Yunlu FENG
;
Qiang WANG
;
Qingwei JIANG
;
Dongsheng WU
;
Xi WU
;
Aiming YANG
Author Information
1. 中国医学科学院北京协和医学院 北京协和医院消化内科，北京 100730
- Keywords:
Pancreatic pseudocyst;
Disconnected pancreatic duct syndrome;
Endoscopic ultrasonography;
Transmural drainage;
Transpapillary pancreatic duct stent placem
- From:
Chinese Journal of Digestive Endoscopy
2024;41(7):537-542
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To assess the efficacy of endoscopic transmural drainage, transpapillary drainage and their combination in reducing cyst recurrence in patients with disconnected pancreatic duct syndrome (DPDS).Methods:A retrospective study was conducted involving 22 patients diagnosed as having DPDS in Peking Union Medical College Hospital from January 2018 to December 2022. Patient data including clinical information, imaging characteristics, drainage technique, complications, and outcomes were extracted from the medical records and telephone follow-up.Results:There were 27 endoscopic treatments in 22 patients, which were categorized into 3 groups based on the procedural approach: transmural in 11 cases, transpapillary in 8, and the combination of both in 8. The combined drainage group exhibited a significantly higher drainage success rate (100.0%, 8/8) compared with the transpapillary group (50.0%, 4/8, P=0.012), with no significant difference compared with the transmural group [90.9% (10/11), P=0.621]. The one-year recurrence rate was significantly lower in the combined drainage group [0.0% (0/8)] than that in the transmural drainage group [55.6% (5/9), P=0.018], and transpapillary drainage alone [42.9% (3/7)] though it did not reach significance ( P=0.085). No significant differences were observed in treatment success rate [45.5% (5/11), 75.0% (6/8) and 87.5% (7/8), H=3.890, P=0.143], or complication incidence [54.5% (6/11), 75.0% (6/8) and 25.0% (2/8), H=3.909, P=0.142]. Conclusion:Transmural drainage combined with pancreatic duct stent placement results in satisfactory drainage of cystic fluid in the short term and significantly reduces one-year recurrence among patients with DPDS.
