Status and influencingfactors of PICCrelated thrombosis in lung cancer patients undergoing cancer chemotherapy
10.3760/cma.j.cn115682-20220128-00485
- VernacularTitle:肺癌化疗患者PICC相关性血栓的现状及影响因素分析
- Author:
Lu LIU
1
;
Ping HU
;
Guojun ZHANG
Author Information
1. 郑州大学第一附属医院呼吸内一科，郑州 450000
- Keywords:
Lung neoplasms;
Catheter-related thrombosis;
Peripherally inserted central catheters;
Influencing factors
- From:
Chinese Journal of Modern Nursing
2022;28(36):5089-5093
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the status and influencing factors of peripherally inserted central catheters (PICC) related thrombosis in lung cancer patients undergoing chemotherapy.Methods:From June to December 2020, a total of 259 lung cancer patients undergoing chemotherapy in the First Affiliated Hospital of Zhengzhou University were enrolled using the convenient sampling method, and the occurrence of PICC related thrombosis within 3 months was recorded. Patients were divided into the thrombus group (18 cases) and the non-thrombosis group (241 cases) according to the occurrence of PICC associated thrombus. Univariate and multivariate Logistic regression analysis were used to explore the influencing factors of PICC related thrombosis in lung cancer patients undergoing chemotherapy.Results:The incidence of PICC related thrombosis of 259 lung cancer patients undergoing chemotherapy was 6.95% (18/259). Univariate analysis showed that there were significant differences in lung cancer stage, pathological type, complications, catheter placement limb, central venouscatheter material, catheter tip position, fibrinogen (Fg) and D-dimer (D-D) between the thrombosis group and the non-thrombotic group ( P<0.05). Multivariate Logistic regression analysis showed that Ⅲ-Ⅳ stage lung cancer, polyurethanecatheter, catheter tip position was 2/3 upper of the superior vena cava, Fg>4 g/L and D-D>0.4 mg/L were the influencing factors of PICC related thrombus in lung cancer patients undergoing chemotherapy ( P<0.05) . Conclusions:PICC related thrombosis in lung cancer patients undergoing chemotherapy is related to lung cancerstage, central venous cathetermaterial, catheter tipposition, Fg and DD. Medical staff should select appropriate catheter materialfor the patients, monitor coagulation-related factors closely, so as to reduce the risk of PICCrelated thrombosis.
