Comparison of AAA and AXB algorithms for dosimetric differences in craniospinal VMAT of pediatric medulloblastoma
10.19745/j.1003-8868.2024049
- VernacularTitle:AAA和AXB算法在儿童髓母细胞瘤全脑全脊髓VMAT中的剂量学差异
- Author:
Li ZHOU
1
;
Yue LIU
Author Information
1. 自贡市第一人民医院儿科,四川自贡 643000
- Keywords:
anisotropic analytical algorithm;
acuros external beam algorithm;
pediatric medulloblastoma;
craniospinal;
volu-metric modulated arc therapy
- From:
Chinese Medical Equipment Journal
2024;45(3):56-60
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the dosimetric difference of anisotropic analytical algorithm(AAA)and acuros external beam(AXB)algorithm in craniospinal volumetric modulated arc therapy(VMAT)planning for pediatric medulloblastoma.Methods Thirty-five pediatric medulloblastoma patients who received craniospinal iradiation(CSI)at some hospital from February 2015 to August 2022 were selected retrospectively.Varian Eclipse 15.6 planning system was used to formulate AAA plans and AXB plans for each of the 35 pediatric patients,which were included in an AAA plan group and an AXB plan group,respectively.Comparison between the AXB plan group and the AAA plan group in dosimetric effect was carried out in terms of Dmean and D2 of planning target volume(PTV),conformity index(CI),homogeneity index(HI),Dmean of organs at risk(OARs)such as bilateral eyeballs,heart,bilateral kidneys and liver,V5,V10,V20 and Dmean of bilateral lungs and Dmax of bilateral lens,bilateral optic nerves and small intestine.Results The AAA plan group had the value of CI significantly lower than that of the AXB plan group(P＜0.05),while the values of HI,D2 and Dmean obviously higher than those of the other group(P＜0.05).The values of Dmean of bilateral eyeballs were statistically higher than those of the AXB plan group(P＜0.05),and the values of V5,V10 and Dmean of bilateral lungs were also higher significantly(P＜0.05).There were no significant differences between the remained dosimetric parameters of OARs of the two groups(P＞0.05).Conclusion AXB applied in CSI planning improves the homogeneity of the dose to the target area and effectively reduces the rates of side effects due to radiation therapy when compared with AAA,and it's recommended that AXB be used instead of AAA in craniospinal VMAT for pediatric medulloblastoma.[Chinese Medical Equipment Journal,2024,45(3):56-60]
