Pay attention to transfusion transmitted virus and ensure the transfusion safety
10.3760/cma.j.cn112866-20230221-00016
- VernacularTitle:关注输血传播病毒并保障输血安全
- Author:
Xiangyan HUANG
1
Author Information
1. 联勤保障部队第九六〇医院输血医学科（解放军济南血液中心），济南 250031
- Keywords:
Transfusion transmitted infection;
Virus;
Transfusion safety;
Strategy
- From:
Chinese Journal of Experimental and Clinical Virology
2023;37(4):353-356
- CountryChina
- Language:Chinese
-
Abstract:
Viral transfusion transmitted infection (TTI) is the biggest threat to the safety of blood transfusion. In order to ensure blood safety, virus detection strategies of blood donors are constantly evolving. The development of serology and nucleic acid detection technology for hepatitis B virus (HBV), hepatitis C virus (HCV) and human immunodeficiency virus (HIV) has effectively reduced the risk of transmission, but blood donation in the window period of infection, occult hepatitis B virus infection (OBI) and antiretroviral HIV treatment period still constantly threatens the transfusion safety. The potential transmission risk of other known viruses and new viruses transmitted through blood transfusion is a new challenge to the transfusion safety. Blood collection and supply institutions should develop better blood safety strategies to reduce the risk of viral TTI by selecting and recruiting low-risk unpaid blood donors, health consultation, using highly sensitive and specific detection technologies and method, inactivating blood components and establishing a complete early warning system.
