Analysis of related factors affecting motor subtypes of Parkinson’s disease
- VernacularTitle:影响帕金森病运动亚型的相关因素分析
- Author:
Wenting ZHAO
1
;
Xinyan YI
1
;
Xuan ZHANG
1
Author Information
- Publication Type:Journal Article
- Keywords: Parkinson; PIGD; Motor subtypes
- From: Journal of Apoplexy and Nervous Diseases 2020;37(5):419-423
- CountryChina
- Language:Chinese
- Abstract: Objective To investigate the differences between the subtypes of postural instability gait difficulty （PIGD） subtypes. in Parkinson’s disease and the subtypes of tremor and the related factors affecting the phenotypes of Parkinson’s disease. Methods Collect hospital between January 2019 and January 2020 in our hospital nursing of 69 patients with Parkinson’s disease，Parkinson’s disease is divided into PIGD and TD groups to evaluate clinical data acquisition and scale，scale including Hoehn-Yahr scale，MDS - UPDRS scale，non-motor symptoms scale （NMSS），Parkinson’s disease sleep scale （PDSS），Mini-mental State Examination （MMSE） and Hamilton Depression Scale （HAMD），Hamilton anxiety scale （HAMA），Parkinson’s life quality evaluation scale （PDQ-39）.The collected data were statistically analyzed. Results There was no statistically significant difference between the two groups in age of onset，course of disease，equivalent dose of levodopa，HAMA，HAMD，MMSE，PDSS，NMSS and PDQ-39 scores. Differences were statistically significant in age of onset，education，medical comorbidities，UPDRS score，H-Y rating，stiffness，bradykinesia，tremor，and gait abnormalities. The next step of correlation analysis found that patients’ age of onset，comorbidity severity，H-Y classification，UPDRS score，and exercise symptoms were correlated with PD subtypes. Conclusion The age of onset，the severity of medical comorbidities，disease severity，and motor subtypes of PD patients were related factors affecting the PIGD subtypes.
- Full text:2024080123301399051影响帕金森病运动亚型的相关因素分析.pdf
