A review of early identification and conversion studies of event-related potentials in individuals with high risk of schizophrenia

VernacularTitle:事件相关电位对精神分裂症高危人群早期识别及转化研究(综述)
Author: Nianchun GUO ^{1
,

2} ; Jing WANG ; Xin YU
Author Information

1. 北京大学第六医院,北京大学精神卫生研究所,国家卫生健康委员会精神卫生学重点实验室(北京大学),国家精神心理疾病临床医学研究中心(北京大学第六医院),北京 100083
2. 石家庄市第八医院,石家庄 050081
Keywords: schizophrenia; clinical high-risk; event-related potentials; review
From: Chinese Mental Health Journal 2024;38(3):200-205
CountryChina
Language:Chinese
Abstract: There is a clinical high-risk period(CHR)before the onset of schizophrenia.Early detection and early treatment are crucial for the prognosis of the disease.Event-related potential(ERP)is a special brain evoked potential.Different ERP components can reflect the neuroelectrophysiological changes of the brain in different cog-nitive processes.Exploring the ERP components of CHR abnormalities may have an important role in the early rec-ognition of diseases and transformation risk.This review found that P300 and MMN have predictive effects on the risk of mental illness conversion,while other ERP components such as P50,Pl.and N400 require more research to verify their reliability as risk markers for mental illness conversion in high-risk populations.